A new drug to prevent heart damage after a stroke has been developed by researchers

In a press release from the University of Guelph, a drug developed by a team of researchers led by Professor Tami Martino and student Christine Reitz was defined as a “potential drug for the treatment of heart attacks” and as a weapon to combat heart failure.

The researchers have actually discovered a possible new pharmacological target, which underlies the recovery processes carried out by the body after a heart attack. Heart attacks can, in fact, cause an inflammatory reaction that can lead to heart damage. This damage can lead to the development of heart failure, for which there is currently no cure.

The drug, called SR9009, targets a key component of the circadian cellular mechanism, interrupting the expression of those genes that trigger an immune response after a heart attack that may be negative in the long term.

The potential drug already tested on mice should be taken a few hours after the attack. Once this is done, patients can avoid taking heart medication for the rest of their lives, which can be exhausting in many cases.

Martino speaks for herself about “exciting” research and a drug that does not seem to be able to harm the heart as a result of a heart attack: “People can survive a heart attack because the heart won’t even be damaged,” says Martino in a press release.

Links:

https://medicalxpress.com/news/2019-10-potential-drug-heart.html

https://www.nature.com/articles/s42003-019-0595-z